BDBM27504 4-HQN::4-hydroxyquinazoline::CHEMBL266540::quinazolin-4-ol

SMILES O=c1[nH]cnc2ccccc12

InChI Key InChIKey=QMNUDYFKZYBWQX-UHFFFAOYSA-N

Data  6 KI  6 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27504   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM27504(4-HQN | 4-hydroxyquinazoline | CHEMBL266540 | quin...)
Affinity DataIC50:  3.45E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed